|
| 用途 | 新药研发 |
| 英文名称 | Amino-PEG5-azide |
| 型号 | BK02304 |
| 包装规格 | |
| 外观 | 淡黄色液体 |
| CAS编号 | 951671-92-4 |
| 别名 | |
| 纯度 | 95% |
| 分子式 | C10H22N4O4 |
| 重金属 | ppm |
Amino-PEG4-Azide With Cas.951671-92-4 Is For Chemial Modifications
Item#: | BK02304 |
CAS#: | 951671-92-4 |
M.F.: | C10H22N4O4 |
M.W.: | 262.31 |
Appearance: | Transparent and oil free liquid |
Purity: | 95% |
Storage: | -20℃ for Long Term |
Synonyms:
O - ( 2 - AMinoethyl ) - O ' - ( 2 - azidoethyl ) triethylene Glycol ; 14 - Azido - 3 , 6 , 9 , 12 -tetraoxatetradecan - 1- aMine ; Azido - PEG4 - Amine ; Amino - PEG5 - azide.
Introduction
The Amino-PEG4-Azide With Cas.951671-92-4 is used for modifying proteins or surfaces such as beads, nanoparticles and self-assembled monolayers. Modification of proteins adds polyethylene glycol (PEG)n spacers, which impart increased water solubility, reduced immunogenicity of the labeled molecule and enhanced in vivo stability in solution. Functionalization of solid surfaces, such as quantum dots, self-assembled monolayers and nanoparticles, with polyethylene glycol spacers significantly reduces nonspecific protein binding. (PEG)n amine reagents used with (PEG)n amine reagents in surface modification can form a hydrophilic “lawn” of methyl ether-terminated PEGs with periodic exposed carboxy-terminated PEGs. The exposed carboxy groups can be coupled to affinity ligands using the carbodiimide coupling reaction with EDC and sulfo-NHS.
Typical PEGylation reagents contain heterogeneous mixtures of different PEG chain lengths; however, our PEGylation reagents are homogenous compounds of defined molecular weight and spacer length, providing precision in optimizing modification applications.
