MS-PEG9-T-Butyl ester Is For PEGyation

Features:

1, MS-PEG9-T-Butyl ester is Colorless to straw-colored liquid with a mild odor. Sinks and mixes with water.

2, It is Stable, Combustible. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides.

3, PEG is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.

4, They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior.

5, They may initiate the polymerization of isocyanates and epoxides.

PEG polymers contain numerous inherent favorable biological characteristics including high water solubility and a lack of toxicity and immunogenicity. Thus, the chemical modification of biologically active compounds, such as peptides, antibody fragments, enzymes, or small molecules with polyethylene glycol chains, referred to as “PEGylation”, often leads to improved pharmacokinetics and biological function in many applications.